Category: Myths & Debunks
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CoQ10 has eight human cognitive trials, about half of them null, and its biggest high-dose neurological trial was stopped for futility.
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Cocoa flavanols and memory: COSMOS tested 500 mg a day for three years in over 5,700 people and found no cognitive effect at all.
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Two prevention trials of ginkgo, GEM and GuidAge, enrolled almost 6,000 people between them over five to six years. Neither reduced dementia.
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Racetams, noopept and phenibut are not lawful US dietary ingredients. FDA has issued warning letters, and one analysis found five such drugs in supplements.
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FDA concluded vinpocetine is not a lawful dietary ingredient and warned women of childbearing age to avoid it. Here is the documentation.
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A federal court ordered Prevagen’s marketer to stop its memory claims in December 2024. What apoaequorin is, and what the trial evidence shows.
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Vitamin B6 above 100 mg a day can cause sensory neuropathy, with cases reported at 50 mg. The doses, the symptoms, and where the dose hides.
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Supplements can make thinking worse: sedation, high-dose B6 neuropathy, masked B12 deficiency, liver injury and disrupted sleep. The documented list.
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Nine label entries that mark a brain supplement as unevidenced, from four ingredients FDA says are not lawful to high-dose vitamin B6.
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The big trials of brain supplements mostly failed. Here is the evidence against buying one, from a site that reviews them for a living.